Validity Testing of Predictive Algorithms Lead Investigator: Anitha Rao-Frisch Institution : Neurocern E-Mail : araofrisch@gmail.com Proposal ID : 522 Proposal Description: Presently there is shortage of neurologists, and specifically neurologists with dementia training (Faulkner et al, 2010). Most patients and families have limited access to expert centers such as ADRCs. Adding to the problem, literature review has indicated that primary care physicians have poor knowledge in dementia evaluation and treatment (Bradford et al. 2009) 1. Our work comprises of testing predictive algorithms using computational means against NACC data. 2. We plan to calculate sensitivity, specificity, false positive, and false negative results of our algorithms for the main cognitive disorders. 3. Using validity scores we plan to tailor algorithms for optimal differentiation of cognitive disorders in order to build clinical decision support software and dementia management tools.